小鼠抗EIF4A1单克隆抗体

Background:

ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Applications:

WB

Name of antibody:

EIF4A1

Immunogen:

Fusion protein of human EIF4A1

Full name:

eukaryotic translation initiation factor 4A1

Synonyms:

DDX2A; EIF4A; EIF-4A; eIF4A-I; eIF-4A-I

SwissProt:

P60842

WB Predicted band size:

46 kDa

WB Positive control:

293T, 231, Hela, HepG2, K562 cell, Mouse liver tissue, Mouse brain tissue lysates

WB Recommended dilution:

1000-5000