兔抗IL7多克隆抗体

Background:

The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.

Applications:

ELISA, WB, IHC

Name of antibody:

IL7

Immunogen:

Synthetic peptide of human IL7

Full name:

interleukin 7

Synonyms:

IL-7

SwissProt:

P13232

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human ovarian cancer and Human thyroid cancer

IHC Recommend dilution:

30-150

WB Predicted band size:

20 kDa

WB Positive control:

Human kidney tissue and Mouse kidney tissue lysates

WB Recommended dilution:

200-1000