兔抗KCNE3多克隆抗体

Background:

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis.

Applications:

ELISA, IHC

Name of antibody:

KCNE3

Immunogen:

Fusion protein of human KCNE3

Full name:

potassium voltage-gated channel subfamily E regulatory subunit 3

Synonyms:

HYPP; HOKPP; MiRP2

SwissProt:

Q9Y6H6

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

50-300