兔抗DUSP2多克隆抗体

Background:

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.

Applications:

ELISA, WB, IHC

Name of antibody:

DUSP2

Immunogen:

Synthetic peptide of human DUSP2

Full name:

dual specificity phosphatase 2

Synonyms：

PAC1; PAC-1

SwissProt:

Q05923

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer and Human liver cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

34 kDa

WB Positive control:

Hela cells

WB Recommended dilution:

200-1000