小鼠抗FGG单克隆抗体

Background:

The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul

Applications:

WB, IF

Name of antibody:

FGG

Immunogen:

Fusion protein of human FGG

Full name:

fibrinogen gamma chain (FGG), transcript variant gamma-A

Synonyms:

fibrinogen, gamma chain; fibrinogen, gamma polypeptide; fibrinogen gamma chain

SwissProt:

P02679

WB Predicted band size:

52 kDa

WB Positive control:

HepG2 cell lysate

WB Recommended dilution:

500-2000