兔抗MED1(Phospho-Thr1457)多克隆抗体

Background:

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1.

Applications:

WB

Name of antibody:

MED1(Phospho-Thr1457)

Immunogen:

Peptide sequence around phosphorylation site of Threonine 1457 (A-Y-T(p)-P-Q) derived from Human PPAR-BP.

Full name:

mediator complex subunit 1

Synonyms：

PBP; CRSP1; RB18A; TRIP2; PPARBP; CRSP200; DRIP205; DRIP230; PPARGBP; TRAP220

SwissProt:

Q15648

WB Predicted band size:

168 kDa

WB Positive control:

Huvec cells lysates treated with serum

WB Recommended dilution:

500-1000