兔抗CEBPA(Phospho-Thr230)多克隆抗体

Background:

This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013]

Applications:

WB

Name of antibody:

CEBPA(Phospho-Thr230)

Immunogen:

Peptide sequence around phosphorylation site of threonine 230 (P-P-T(p)-P-V) derived from Human C/EBP-α.

Full name:

CCAAT/enhancer binding protein (C/EBP), alpha

Synonyms：

CEBP; C/EBP-alpha

SwissProt:

P49715

WB Predicted band size:

38 kDa

WB Positive control:

COS7 cells lysates

WB Recommended dilution:

500-1000