小鼠抗ARHGDIB单克隆抗体

Background:

Members of the Rho (or ARH) protein family and other Ras-related small GTP-binding proteins are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases.

Applications:

ELISA, WB

Name of antibody:

ARHGDIB

Immunogen:

Fusion protein of human ARHGDIB

Full name:

Rho GDP dissociation inhibitor beta

Synonyms:

D4; GDIA2; GDID4; LYGDI; Ly-GDI; RAP1GN1; RhoGDI2

SwissProt:

P52566

WB Predicted band size:

23 kDa

WB Positive control:

Jurkat whole cell lysate

WB Recommended dilution:

500-2000