小鼠抗AKR1B1单克隆抗体

Background:

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.

Applications:

WB

Name of antibody:

AKR1B1

Immunogen:

Fusion protein of human AKR1B1

Full name:

aldo-keto reductase family 1 member B

Synonyms:

AR; ADR; ALR2; ALDR1

SwissProt:

P15121

WB Predicted band size:

36 kDa

WB Positive control:

C6, 3T3, Jurkat and Hela cell lysates

WB Recommended dilution:

1000-5000