兔抗ZNF395多克隆抗体

Background:

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF395 (Zinc finger protein 395), also known as PBF (Papillomavirus-binding factor) and HDBP2 (Huntington disease gene regulatory region-binding protein 2), is a 513 amino acid protein that contains one C2H2-type zinc finger. ZNF395 binds to the 3’-CCGG-5’ sequence within the papillomavirus promoter adjacent to a RUNX1-binding motif. It has also been established that ZNF395 binds to a seven base pair region within the Huntington's disease (HD) gene promoter, an essential element for HD gene expression. ZNF395 is widely expressed and probably shuttles between the nucleus and cytoplasm.

Applications:

ELISA, IHC

Name of antibody:

ZNF395

Immunogen:

Synthetic peptide of human ZNF395

Full name:

zinc finger protein 395

Synonyms：

PBF; PRF1; HDBP2; PRF-1; HDBP-2; HDRF-2; Si-1-8-14

SwissProt:

Q9H8N7

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human ovarian cancer

IHC Recommend dilution:

50-200