小鼠抗MPI单克隆抗体

Background:

Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. Alternative splicing results in multiple transcript variants.

Applications:

WB, IF

Name of antibody:

MPI

Immunogen:

Fusion protein of human MPI

Full name:

mannose phosphate isomerase

Synonyms:

PMI; PMI1; CDG1B

SwissProt:

P34949

WB Predicted band size:

47 kDa

WB Positive control:

Rat brain tissue, Rat kidney tissue, A549 and Lncap cell lysates

WB Recommended dilution:

1000-5000

IF positive control:

Hela cells

IF Recommend dilution:

150-300