兔抗BIRC3多克隆抗体

Background:

This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.

Applications:

ELISA, IHC

Name of antibody:

BIRC3

Immunogen:

Fusion protein of human BIRC3

Full name:

baculoviral IAP repeat containing 3

Synonyms:

AIP1; API2; MIHC; CIAP2; HAIP1; HIAP1; IAP-1; MALT2; RNF49; c-IAP2

SwissProt:

Q13489

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and Human tonsil

IHC Recommend dilution:

100-200