中文名称:兔抗CDKN2AIP多克隆抗体
英文名称: Anti-CDKN2AIP rabbit polyclonal antibody
别 名: CARF
抗 原: CDKN2AIP
储 存: 冷冻(-20℃)
宿 主: Rabbit
相关类别: 一抗
反应种属: Human
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background: |
CDKN2AIP (CDKN2A-interacting protein), also known as CARF, is a 580 amino acid protein that activates p53 via p14 ARF (alternate reading frame)-dependent and independent pathways. CDKN2AIP-dependent activation of p53, a protein that up-regulates growth arrest and apoptosis-related genes in response to stress signals, leads to an enhancement of p53 function. Expression levels of CDKN2AIP and p53 show an inverse relationship that is caused by a negative-feedback control via a proteasome-mediated degradation pathway. CDKN2AIP is expressed ubiquitously across tissue samples and, along with p14 ARF, is localized to the perinucleolar region within the nucleus. |
Applications: |
ELISA, IHC |
Name of antibody: |
CDKN2AIP |
Immunogen: |
Fusion protein of human CDKN2AIP |
Full name: |
CDKN2A interacting protein |
Synonyms: |
CARF |
SwissProt: |
Q9NXV6 |
ELISA Recommended dilution: |
1000-5000 |
IHC positive control: |
Human thyroid cancer |
IHC Recommend dilution: |
50-200 |