兔抗PFKM多克隆抗体

Background:

Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.

Applications:

ELISA, IHC

Name of antibody:

PFKM

Immunogen:

Fusion protein of human PFKM

Full name:

phosphofructokinase, muscle

Synonyms:

GSD7; PFK1; PFKA; PFKX; PFK-1; ATP-PFK; PPP1R122

SwissProt:

P08237

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

40-200