兔抗IRS1 (Phospho-Ser312)多克隆抗体

Background:

May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit

Applications:

WB

Name of antibody:

IRS1 (Phospho-Ser312)

Immunogen:

Synthetic peptide of human IRS1 (Phospho-Ser312)

Full name:

insulin receptor substrate 1 (Phospho-Ser312)

Synonyms：

HIRS-1

SwissProt:

P35568

WB Predicted band size:

180 kDa

WB Positive control:

293 cells treated with insulin

WB Recommended dilution:

500-1000