兔抗SLC22A5多克隆抗体

Background:

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy.

Applications:

WB

Name of antibody:

SLC22A5

Immunogen:

Fusion protein of human SLC22A5

Full name:

solute carrier family 22 (organic cation/carnitine transporter), member 5

Synonyms：

CDSP; FLJ46769; OCTN2; OCTN2VT

SwissProt:

O76082

WB Predicted band size:

63 kDa

WB Positive control:

MCF-7 cells

WB Recommended dilution:

500-2000