小鼠抗GRAP2单克隆抗体

Background:

This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Applications:

WB

Name of antibody:

GRAP2

Immunogen:

Fusion protein of human GRAP2

Full name:

GRB2-related adaptor protein 2

Synonyms:

P38; GADS; GRID; GRPL; GrbX; Mona; GRB2L; GRBLG; Grf40; GRAP-2

SwissProt:

O75791

WB Predicted band size:

38 kDa

WB Positive control:

CEM, Molt-4 and Jurkat cell lysates

WB Recommended dilution:

1000-5000