兔抗TEK多克隆抗体

Background:

The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.

Applications:

ELISA, IHC

Name of antibody:

TEK

Immunogen:

Synthetic peptide of human TEK

Full name:

TEK tyrosine kinase, endothelial

Synonyms：

TIE2; VMCM; TIE-2; VMCM1; CD202B

SwissProt:

Q02763

ELISA Recommended dilution:

3000-10000

IHC positive control:

Human liver cancer and Human thyroid cancer

IHC Recommend dilution:

50-200