小鼠抗SPP1单克隆抗体

Background:

The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB

Name of antibody:

SPP1

Immunogen:

Fusion protein of human SPP1

Full name:

secreted phosphoprotein 1

Synonyms:

OPN; BNSP; BSPI; ETA-1; Osteopontin

SwissProt:

P10451

WB Predicted band size:

35 kDa

WB Positive control:

Jurkat whole cell lysate

WB Recommended dilution:

1000-5000