小鼠抗CTSD单克隆抗体

Background:

This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.

Applications:

ELISA, WB

Name of antibody:

CTSD

Immunogen:

Fusion protein of human CTSD

Full name:

cathepsin D

Synonyms:

CPSD; CLN10; HEL-S-130P

SwissProt:

P07339

WB Predicted band size:

45 kDa

WB Positive control:

MCF-7 whole cell lysate

WB Recommended dilution:

1000-5000