兔抗FBH1多克隆抗体

Background:

This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Applications:

ELISA, IHC

Name of antibody:

FBH1

Immunogen:

Fusion protein of human FBH1

Full name:

F-box DNA helicase 1

Synonyms:

Fbx18; hFBH1; FBXO18

SwissProt:

Q8NFZ0

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

100-300