兔抗COX7A2多克隆抗体

Background:

Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14.

Applications:

ELISA, WB, IHC

Name of antibody:

COX7A2

Immunogen:

Synthetic peptide of human COX7A2

Full name:

cytochrome c oxidase subunit 7A2

Synonyms:

VIIAL; COX7AL; COX7AL1; COXVIIAL; COXVIIa-L

SwissProt:

P14406

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer

IHC Recommend dilution:

25-50

WB Predicted band size:

9 kDa

WB Positive control:

Hela cell lysate

WB Recommended dilution:

200-1000