兔抗CETN3多克隆抗体

Background:

The protein encoded by this gene contains four EF-hand calcium binding domains, and is a member of the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a fundamental role in centrosome duplication and separation. Multiple forms of the proteins similar to the yeast centrin have been identified in human and other mammalian cells, some of which have been shown to be associated with centrosome fractions. This protein appears to be one of the most abundant centrins associated with centrosome, which suggests a similar function to its yeast counterpart. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB

Name of antibody:

CETN3

Immunogen:

Full length fusion protein

Full name:

centrin 3

Synonyms:

CEN3; CDC31

SwissProt:

O15182

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

20 kDa

WB Positive control:

TM4, Jurkat, NIH/3T3 and RAW264.7 cell lysates

WB Recommended dilution:

500-2000