小鼠抗CUL4B单克隆抗体

Background:

This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Applications:

WB, IHC

Name of antibody:

CUL4B

Immunogen:

Fusion protein of human CUL4B

Full name:

cullin 4B (CUL4B), transcript variant 1

Synonyms:

CUL-4B; MRXHF2; MRXS15; MRXSC; SFM2

SwissProt:

Q13620

IHC positive control:

human pancreas tissue and carcinoma of human pancreas tissue; carcinoma of human thyroid tissue and carcinoma of human prostate tissue

IHC Recommend dilution:

25-100

WB Predicted band size:

104 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, Jurkat, MDCK, MCF-7 cell lysates

WB Recommended dilution:

1000-5000