兔抗TLE6多克隆抗体

Background:

This gene encodes a member of the Groucho/ transducin-like Enhancer of split family of transcriptional co-repressors. The encoded protein is a component of the mammalian subcortical maternal complex, which is required for preimplantation development. In mouse, knock out of this gene results in cleavage-stage embryonic arrest resulting from defective cytoplasmic F-actin meshwork formation and asymmetric cell division. In human, an allelic variant in this gene is associated with preimplantation embryonic lethality. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

TLE6

Immunogen:

Fusion protein of human TLE6

Full name:

transducin like enhancer of split 6

Synonyms:

GRG6; PREMBL

SwissProt:

Q9H808

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

50-200