| Background: | This gene encodes a member of the Groucho/ transducin-like Enhancer of split family of transcriptional co-repressors. The encoded protein is a component of the mammalian subcortical maternal complex, which is required for preimplantation development. In mouse, knock out of this gene results in cleavage-stage embryonic arrest resulting from defective cytoplasmic F-actin meshwork formation and asymmetric cell division. In human, an allelic variant in this gene is associated with preimplantation embryonic lethality. Alternative splicing results in multiple transcript variants. | 
| Applications: | ELISA, IHC | 
| Name of antibody: | TLE6 | 
| Immunogen: | Fusion protein of human TLE6 | 
| Full name: | transducin like enhancer of split 6 | 
| Synonyms: | GRG6; PREMBL | 
| SwissProt: | Q9H808 | 
| ELISA Recommended dilution: | 5000-10000 | 
| IHC positive control: | Human liver cancer | 
| IHC Recommend dilution: | 50-200 | 
	
	 
 
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