兔抗AIF1多克隆抗体

Background:

This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene. Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

Applications:

ELISA, WB, IHC

Name of antibody:

AIF1

Immunogen:

Full length fusion protein

Full name:

allograft inflammatory factor 1

Synonyms：

IBA1, IRT1, AIF-1, IRT-1

SwissProt:

P55008

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human breast cancer and human cervical cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

17 kDa

WB Positive control:

Mouse kidney tissue

WB Recommended dilution:

200-1000