兔抗SLC8B1多克隆抗体

Background:

Mitochondrial sodium/calcium antiporter that mediates sodium-dependent calcium efflux from mitochondrion, thereby acting as a key regulator of mitochondrion calcium homeostasis. Regulates rates of glucose-dependent insulin secretion in pancreatic beta-cells during the first phase of insulin secretion: acts by mediating efflux of calcium from mitochondrion, thereby affecting cytoplasmic calcium responses. Able to transport Ca2+ in exchange of either Li+ or Na+, explaining how Li+ catalyzes Ca2+ exchange. In contrast to other members of the family its function is independent of K+.

Applications:

ELISA, IHC

Name of antibody:

SLC8B1

Immunogen:

Synthetic peptide of human SLC8B1

Full name:

solute carrier family 8 member B1

Synonyms:

NCLX; NCKX6; SLC24A6

SwissProt:

Q6J4K2

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human liver cancer and human tonsil

IHC Recommend dilution:

25-100