兔抗ERLIN1多克隆抗体

Background:

The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62.

Applications:

ELISA, WB, IHC

Name of antibody:

ERLIN1

Immunogen:

Fusion protein of human ERLIN1

Full name:

ER lipid raft associated 1

Synonyms:

KE04; KEO4; SPFH1; SPG62; Erlin-1; C10orf69

SwissProt:

O75477

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and Human prostate cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

39 kDa

WB Positive control:

Rat pancreas tissue lysate

WB Recommended dilution:

500-2000