兔抗PPP2R2A多克隆抗体

Background:

Protein phosphatase 2A subunit B isoform R2-α (PPP2R2A) is the component of regulatory subunit B of serine/threonine protein phosphatase 2A (PP2A). PPP2R2A belongs to the R2/B55/PR55 family of regulatory subunit B. Evidence suggests that subunit PPP2R2A enhances TGF-β, Activin, and Nodal signaling pathways and may play an important role in cell cycle regulation. PPP2R2A/PP2A, B55-α/PR55-α isoform interacts with the type I TGF-β receptors via unique WD-40 repeats that contribute to the anti-proliferative function of TGF-β receptors.

Applications:

WB

Name of antibody:

PPP2R2A

Immunogen:

Fusion protein of human PPP2R2A

Full name:

protein phosphatase 2, regulatory subunit B, alpha

Synonyms：

B55A; B55ALPHA; PR52A; PR55A

SwissProt:

P63151

WB Predicted band size:

52 kDa

WB Positive control:

Rat brain tissue

WB Recommended dilution:

500-2000