兔抗IL6R多克隆抗体

Background:

This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.

Applications:

ELISA, IHC

Name of antibody:

IL6R

Immunogen:

Synthetic peptide of human IL6R

Full name:

interleukin 6 receptor

Synonyms:

IL6Q; gp80; CD126; IL6RA; IL6RQ; IL-6RA; IL-6R-1

SwissProt:

P08887

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human tonsil

IHC Recommend dilution:

20-100