兔抗NCOR1多克隆抗体

Background:

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.

Applications:

ELISA, IHC

Name of antibody:

NCOR1

Immunogen:

Synthetic peptide of human NCOR1

Full name:

nuclear receptor corepressor 1

Synonyms：

N-CoR, TRAC1, N-CoR1, hN-CoR

SwissProt:

O75376

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human cervical cancer and Human tonsil

IHC Recommend dilution:

100-300