兔抗PSMA1多克隆抗体

Background:

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Applications:

ELISA, WB, IHC

Name of antibody:

PSMA1

Immunogen:

Fusion protein of human PSMA1

Full name:

proteasome subunit alpha 1

Synonyms:

NU; HC2; PROS30; HEL-S-275

SwissProt:

P25786

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human prostate cancer

IHC Recommend dilution:

150-300

WB Predicted band size:

30 kDa

WB Positive control:

SKOV3, 293T, Raji, PC-3, HepG2, Hela and Jurkat cell lysates

WB Recommended dilution:

1000-5000