中文名称: 兔抗IL6ST多克隆抗体
| Background: | The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. | 
| Applications: | ELISA, IHC | 
| Name of antibody: | IL6ST | 
| Immunogen: | Fusion protein of human IL6ST | 
| Full name: | interleukin 6 signal transducer | 
| Synonyms: | CD130; GP130; CDW130; IL-6RB | 
| SwissProt: | P40189 | 
| ELISA Recommended dilution: | 5000-10000 | 
| IHC positive control: | Human esophagus cancer | 
| IHC Recommend dilution: | 30-150 | 
		 
 
	
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