兔抗IL4多克隆抗体

Background:

The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Applications:

WB

Name of antibody:

IL4

Immunogen:

Synthesized peptide derived from C-terminal of human IL4.

Full name:

interleukin 4

Synonyms：

BSF1; IL-4; BCGF1; BSF-1; BCGF-1

SwissProt:

P05112

WB Predicted band size:

17 kDa

WB Positive control:

Hela cells lysate

WB Recommended dilution:

500-3000