兔抗CAMK2B/G多克隆抗体

Background:

Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca2+ transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.

Applications:

WB

Name of antibody:

CAMK2B/G

Immunogen:

Synthesized peptide derived from C-terminal of human CaMK2β/γ.

Full name:

calcium/calmodulin-dependent protein kinase II beta/gamma

Synonyms：

CAM2; CAMK2; CAMKB/CAMK; CAMKG; CAMK-II

SwissProt:

Q13555/Q13554

WB Predicted band size:

63/73 kDa

WB Positive control:

Jurkat cells and COLO205 lysates

WB Recommended dilution:

500-3000