兔抗IFIH1多克隆抗体

Background:

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19.

Applications:

WB

Name of antibody:

IFIH1

Immunogen:

Synthesized peptide derived from C-terminal of human IFIH1.

Full name:

interferon induced with helicase C domain 1

Synonyms：

AGS7; Hlcd; MDA5; MDA-5; RLR-2; IDDM19

SwissProt:

Q9BYX4

WB Predicted band size:

117 kDa

WB Positive control:

Jurkat cells lysate

WB Recommended dilution:

500-3000