兔抗CST4多克隆抗体

Background:

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a type 2 salivary cysteine peptidase inhibitor. The protein is an S-type cystatin, based on its high level of expression in saliva, tears and seminal plasma. The specific role in these fluids is unclear but antibacterial and antiviral activity is present, consistent with a protective function.

Applications:

ELISA, WB

Name of antibody:

CST4

Immunogen:

Fusion protein of human CST4

Full name:

cystatin S

SwissProt:

P01036

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

16 kDa

WB Positive control:

Human liver cancer tissue lysate

WB Recommended dilution:

500-2000