小鼠抗SORL1单克隆抗体

Background:

This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded preproprotein is proteolytically processed to generate the mature receptor, which likely plays roles in endocytosis and sorting. Mutations in this gene may be associated with Alzheimer's disease.

Applications:

WB

Name of antibody:

SORL1

Immunogen:

Fusion protein of human SORL1

Full name:

sortilin related receptor 1

Synonyms:

LR11; LRP9; SORLA; gp250; SorLA-1; C11orf32

SwissProt:

Q92673

WB Predicted band size:

248 KD

WB Positive control:

SH-SY5Y cell, Rat brain tissue lysates

WB Recommended dilution:

500-2000