兔抗HDAC1(Phospho-Ser421) 多克隆抗体

Background:

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation.

Applications:

WB

Name of antibody:

HDAC1(Phospho-Ser421)

Immunogen:

Peptide sequence around phosphorylation site of Serine 421 (E-F-S(p)-D-S) derived from Human HDAC1.

Full name:

histone deacetylase 1

Synonyms：

HD1; RPD3; GON-10; RPD3L1

SwissProt:

Q13547

WB Predicted band size:

55 kDa

WB Positive control:

HepG2 cells lysates

WB Recommended dilution:

500-1000