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021-54845833/15800441009
中文名称：兔抗BAGE2多克隆抗体
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Background: |
Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22% of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
BAGE2 |
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Immunogen: |
Synthetic peptide of human BAGE2 |
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Full name: |
B melanoma antigen family member 2 |
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Synonyms: |
CT2.2 |
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SwissProt: |
Q86Y30 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
12 kDa |
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WB Positive control: |
A375 cell lysate |
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WB Recommended dilution: |
200-1000 |
