兔抗HDAC1多克隆抗体

Background:

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

Applications:

ELISA, IHC

Name of antibody:

HDAC1

Immunogen:

Fusion protein of human HDAC1

Full name:

histone deacetylase 1

Synonyms：

HD1; RPD3; GON-10; RPD3L1

SwissProt:

Q13547

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human breast cancer and human thyroid cancer

IHC Recommend dilution:

25-100