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技术规格
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Background: |
INDOL1 is also known as IDO2 (indoleamine 2,3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2,3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
IDO2 |
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Immunogen: |
Full length fusion protein |
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Full name: |
indoleamine 2,3-dioxygenase 2 |
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Synonyms： |
INDOL1 |
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SwissProt: |
Q6ZQW0 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human brain |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
45 kDa |
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WB Positive control: |
Human fetal brain tissue and Human kidney tissue |
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WB Recommended dilution: |
500-2000 |
