兔抗ACLY多克隆抗体

Background:

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.

Applications:

ELISA, WB

Name of antibody:

ACLY

Immunogen:

Fusion protein of human ACLY

Full name:

ATP citrate lyase

Synonyms：

ACL; ATPCL; CLATP

SwissProt:

P53396

ELISA Recommended dilution:

2000-5000

WB Predicted band size:

121 kDa

WB Positive control:

A172 and PC3 cells

WB Recommended dilution:

500-2000