小鼠抗IGF2BP3单克隆抗体

Background:

The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.

Applications:

WB

Name of antibody:

IGF2BP3

Immunogen:

Fusion protein of human IGF2BP3

Full name:

insulin like growth factor 2 mRNA binding protein 3

Synonyms:

KOC; CT98; IMP3; KOC1; IMP-3; VICKZ3

SwissProt:

O00425

WB Predicted band size:

64 kDa

WB Positive control:

MCF7, SKVO3, NTERA2, Jurkat, K562 and Hela cell lysates

WB Recommended dilution:

1000-5000