小鼠抗FERMT3单克隆抗体

Background:

Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Applications:

WB, IHC

Name of antibody:

FERMT3

Immunogen:

Fusion protein of human FERMT3

Full name:

fermitin family member 3

Synonyms:

URP2; KIND3; MIG-2; MIG2B; URP2SF; UNC112C

SwissProt:

Q86UX7

IHC positive control:

Human tonsil tissue

IHC Recommend dilution:

50-150

WB Predicted band size:

76 KD

WB Positive control:

Jurkat cell lysate

WB Recommended dilution:

200-1000