小鼠抗ATRIP单克隆抗体

Background:

The product of this gene is an essential component of the DNA damage checkpoint, and binds to single-stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Applications:

WB, IHC, IF, FC

Name of antibody:

ATRIP

Immunogen:

Fusion protein of human ATRIP

Full name:

ATR interacting protein (ATRIP), transcript variant 1

Synonyms:

DKFZp762J2115; FLJ12343; MGC20625; MGC21482; MGC26740

SwissProt:

Q8WXE1

IHC positive control:

adenocarcinoma of human ovary tissue and adenocarcinoma of human endometrium tissue; human kidney tissue and human pancreas tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

86 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, Jurkat, MDCK, PC12, MCF-7 cell lysates

WB Recommended dilution:

500-2000