| Background: | Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. | 
| Applications: | WB, IF | 
| Name of antibody: | TP53 (Phospho-Ser33) | 
| Immunogen: | Synthetic peptide of human TP53 (Phospho-Ser33) | 
| Full name: | tumor protein p53 (Phospho-Ser33) | 
| Synonyms: | P53; BCC7; LFS1; TRP53 | 
| SwissProt: | P04637 | 
| WB Predicted band size: | 44 kDa | 
| WB Positive control: | HT29 cells | 
| WB Recommended dilution: | 500-1000 | 
| IF Positive control: | Hela cells | 
| IF Recommended dilution | 100-200 | 
	
	
 
 
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