小鼠抗CHGA单克隆抗体

Background:

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown. [provided by RefSeq, Jul 2008].

Applications:

WB, IHC, IF

Name of antibody:

CHGA

Immunogen:

Fusion protein of human CHGA

Full name:

chromogranin A (CHGA), transcript variant 1

Synonyms:

CGA

SwissProt:

P10645

IHC positive control:

human pancreas tissue and human liver tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

51 kDa

WB Positive control:

SVT2, A549 cell lysates

WB Recommended dilution:

200-1000