小鼠抗DBN1单克隆抗体

Background:

The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.

Applications:

WB, IHC

Name of antibody:

DBN1

Immunogen:

Fusion protein of human DBN1

Full name:

drebrin 1

Synonyms:

D0S117E

SwissProt:

Q16643

IHC positive control:

Human spleen tissue

IHC Recommend dilution:

500-2000

WB Predicted band size:

71 KD

WB Positive control:

SH-SY5Y cell lysate

WB Recommended dilution:

500-2000