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中文名称 : 小鼠抗TMEM173单克隆抗体
英文名称 : Anti-TMEM173 mouse monoclonal antibody
别 名 : ERIS; hMITA; hSTING; MITA; MPYS; NET23; SAVI; STING
储 存 : 冷冻（-20℃） 避光
宿 主 : Mouse
抗 原 : TMEM173
反应种属 : Human
相关类别 : 一抗
标 记 物 : Unconjugate
克隆类型 : mouse monoclonal
技术规格
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Background: |
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. |
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Applications: |
WB, IHC |
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Name of antibody: |
TMEM173 |
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Immunogen: |
Fusion protein of human TMEM173 |
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Full name: |
transmembrane protein 173 (TMEM173), transcript variant 1 |
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Synonyms: |
ERIS; hMITA; hSTING; MITA; MPYS; NET23; SAVI; STING |
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SwissProt: |
Q86WV6 |
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IHC positive control: |
adenocarcinoma of human ovary tissue and carcinoma of human prostate tissue; carcinoma of human bladder tissue and carcinoma of human lung tissue |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
42 kDa |
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WB Positive control: |
Jurkat cell lysate |
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WB Recommended dilution: |
500-2000 |
